Human Glomerular Microvascular Endothelial Cells (HGMEC)

Background: 

    Primary Human Glomerular Microvascular Endothelial Cells, These Anti Free Human Primary Cells Were Initiated By Decapitated Glomeruli Isolated From Normal Human Kidney Cortical Tissue Without The Use Of Positive Selection Of Antibodies.

Animal Species/Oganism : Human

Tissue And Cell Type:  Renal cortex

Morphology Epithelium-like, adherent growth

Complete Growth Medium And Culture Conditions: Complete Growth Medium And Culture Boost ™ Classic Cell Culture Medium (product No.: 4Z0-500)

Gas Phase: Air, 95%; Carbon Dioxide, 5%. Temperature: 37 ℃. 

Frozen Solution: Cell Freezing Medium (4Z0-705) 

Human Glomerular Microvascular Endothelial Cell (HGMEC) Ex Warehouse Test Index: 

Note: This product is for scientific research only

Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation" Tiemeier et al. Stem Cell Reports, 2019

"Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip" Musah et al. Nature Protocols, 2018

"Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells" Sartain et al. J Biological Chemistry, 2018

"Tacrolimus Prevents von Willebrand Factor Secretion by Allostimulated Human Glomerular Endothelium" Beland et al. Am J Transplantation, 2018

"Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip" Musah et al. Nature and Biological Engineering, 2017

"The formation of quiescent glomerular endothelial cell monolayer in vitro is strongly dependent on the choice of extracellular matrix coating" Pajecka et al. Experimental Cell Research, 2017.

"The human kidney capsule contains a functionally distinct mesenchymal stromal cell population" Leuning et al. PLoS One, 2017.

"Nitrite Activates 5′AMP-Activated Protein Kinase-Endothelial Nitric Oxide Synthase Pathway in Human Glomerular Endothelial Cells" Miyamoto et al. Biol. & Pharma Bulletin, 2017.

"Circulating Fibroblast Growth Factor-2, HIV-Tat, and Vascular Endothelial Cell Growth Factor-A in HIV-Infected Children with Renal Disease Activate Rho-A and Src in Cultured Renal Endothelial Cells"  Das et al. PLoS One, 2016.

"TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human GLomerular Endothelial Cells" Sartain et al. J Immunology, 2016.

"TNF causes changes in glomerular endothelial permeability and morphology through a Rho and myosin light chain kinase-dependent mechanism" Xu et al. Physiological Reports, 2015.

"Factor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings" Turner and Moake, PLoS One, 2015.

"Adenosine Kinase Inhibition Protects The Kidney Against Streptozotocin-Induced Diabetes Through Anti-inflammatory and Anti-oxidant Mechanisms" Pye et al. Pharmacological Research, 2014.

SDS

ACBRI 128