HN4 Human Clear Cell Renal Cell Carcinoma Cell

A rare renal tumor, which occurs in the proximal tubular epithelial cells of the renal cortex. Its histological characteristics are malignant epithelial cells. In the conventional staining method, it has typical transparent cytoplasm. Due to the high content of glycogen and lipid, it presents a nest-like growth pattern. Clinically, it can be manifested as hematuria, abdominal pain, anemia, and in a few cases, it can touch the abdominal mass.

Culture media and additives/Complete Growth Medium and Culture Conditions:

90% DMEM (MD0100)+10% fetal bovine serum (SD0200)+G/A (SD0038)

DMEM complete medium (article number: MD0101)

Gas phase: air, 95%; Carbon dioxide, 5%. Temperature: 37 ℃.

Freezing conditions: basic medium+5% DMSO+20% FBS (SD0200)

Complete cryopreservation solution: non-programmed cooling cell cryopreservation solution (low serum) (SD0001)

Note: This product is for scientific research only

 PubMed=8603355; DOI=10.1016/0165-4608(95)00201-4

Bergerheim U.S.R., Soderhall M., Zabarovsky E.R., Franzen B., Manneborg-Sandlund A., Li C., Jacobson S.H., Auer G., Klein G., Collins V.P.

Genotypic and phenotypic characterization of two newly established renal cell carcinoma cell lines.

Cancer Genet. Cytogenet. 86:95-101(1996)