MNT-1 Human melanoma cells

Human melanoma cell MNT-1, also known as MNT1 or MNT. This cell is a type of human melanoma cell isolated from lymph nodes in melanoma patients, exhibiting fibroblast morphology. This cell is susceptible to human parapulmonary virus (HMPV) and can be used for research on melanosome characteristics, melanosome formation, effects on human pigmentation, and membrane transport.

Animal Species: Human 

Tissue Source:Skin，Melanoma

Morphology:fibroblast-like, adherent growth

Culture Medium Formula:69% DMEM (MD0100)+20% fetal bovine serum (SD0200)+10%AIM-V+1%NEAA(SD0046)+G/A (SD0038)

Gas phase: Air, 95%; Carbon dioxide, 5%. Temperature: 37℃. 

Freezing conditions:  90% FBS (SD0200) + 10% DMSO

Complete cryopreservation solution: No Programmed Cryopreservation Cells Solution (low Serum)(SD0001)

Declaration: The product is for scientific research purposes only.

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PubMed=12417263; DOI=10.1016/S0006-2952(02)01353-9
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Cytotoxicity of dopamine-derived tetrahydroisoquinolines on melanoma cells.
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PubMed=25950383; DOI=10.1111/pcmr.12380
Ikrame Lazar, Emily Clement, Manuelle Ducoux-Petit, Laurence Denat, Vanessa Soldan, Stephanie Dauvillier, Stephanie Balor, Odile Burlet-Schiltz, Lionel Larue, Catherine Muller, Laurence Nieto;
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
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PubMed=28940687; DOI=10.1111/1348-0421.12542
Ko Sato, Oshi Watanabe, Suguru Ohmiya, Fumiko Chiba, Akira Suzuki, Michiko Okamoto, Jiang Younghuang, Akihiro Hata, Hiroyuki Nonaka, Setsuko Kitaoka, Yukio Nagai, Kazuhisa Kawamura, Masahiro Hayashi, Satoru Kumaki, Tamio Suzuki, Kazuyoshi Kawakami, Hidekazu Nishimura;
Efficient isolation of human metapneumovirus using MNT-1, a human malignant melanoma cell line with early and distinct cytopathic effects.
Microbiol. Immunol. 61:497-506(2017)