G418 100x

 G418 is an aminoglycoside antibiotic produced by Micromonospora rubra and similar in structure to gentamicin B1. It is used for the selection and maintenance of eukaryotic cells expressing neo gene. It blocks protein synthesis by inhibiting the genes of transposons Tn601 and Tn5, interfering with the function of ribosomes, and produces toxins to prokaryotic and eukaryotic cells, including bacteria, yeast, plant and mammalian cells, as well as protozoa and worms. When the neo gene is integrated into the eukaryotic DNA, it can start the transcription of the sequence encoded by the neo gene into mRNA, so as to obtain the efficient expression of the resistant product aminoglycoside phosphotransferase, so that the cell can obtain resistance and grow in the selective medium containing G418.

Storage temperature: - 20 ℃. Repeated freezing and thawing will affect the use efficacy of the product, and the system is established for sub-packaging and storage

Note: This product is only used for scientific research