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Rat Cochlear Microglia Cell Line (Mocha)
No.:IM057
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Products Description
Background: Mocha Cells Are A Rat Cochlear Microglial Cell Line They Were Developed From An Immunomagnetically Enriched Population Of CD11b+ Cells From P3 Rat Cochlea And Immortalised With The 12S E1A Gene Of Adenovirus In A Replication-incompetent Retroviral Vector.Microglia Are A Unique Lineage Of Mononuclear Phagocytic Cells That Play An Essential Role In Development, Immunological Defense And In- Flammatory Processes In The Central Nervous System. Microglia Account For 10-15% Of All Cells Found Within The Brain. As The Resident Macroscopic Cells, They Act As The First And Main Form Of Active Immune Defense In The Central Nervous System (CNS). They Were Cultured From Immunomagnetic Enriched CD11b+cells In P3 Rat Cochlea And Immortalized In Adenovirus 12S E1A Gene In A Retroviral Vector Without Replication Ability. Microglia Is A Unique Mononuclear Phagocyte Lineage, Which Plays An Important Role In The Development, Immune Defense And Combustion Of The Central Nervous System. Microglia Account For 10-15% Of All Cells In The Brain. Macrophages, As Macrophages In The Body, Are The First And Main Form Of Active Immune Defense In The Central Nervous System (CNS). Animal Species/Oganism & Nbsp; Rat Tissue Source; Tissue And Cell Type Morphology Of Cochlear Microglia; Wall Attached Growth& Nbsp; Note: This Product Is Only For Scientific Research