MHCC97-L Human Hepatoma Cell (low Conversion)

Established by Wuhan Tongji University, MHCC97 clone with low transfer potential.

Animal species/Organism Human

Tissue and Cell Type: liver

Morphology epithelial cell-like, adherent growth

Culture media and additives/Complete Growth Medium and Culture Conditions:

DMEM high sugar (MD0100)+10% FBS (SD0200)+1% G/A (SD0038)

Complete medium: DMEM high sugar complete medium (MD0101)

Gas phase: air, 95%; Carbon dioxide, 5%. Temperature: 37 ℃.

Note: This product is for scientific research only

PubMed=11819844; DOI=10.3748/wjg.v7.i5.630
Li Y., Tang Z.-Y., Ye S.-L., Liu Y.-K., Chen J., Xue Q., Chen J., Gao D.-M., Bao W.-H.
Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97.
World J. Gastroenterol. 7:630-636(2001)

PubMed=15048980; DOI=10.1002/pmic.200300653
Ding S.-J., Li Y., Shao X.-X., Zhou H., Zeng R., Tang Z.-Y., Xia Q.-C.
Proteome analysis of hepatocellular carcinoma cell strains, MHCC97-H and MHCC97-L, with different metastasis potentials.
Proteomics 4:982-994(2004)

PubMed=15146329; DOI=10.1007/s00432-004-0564-9
Li Y., Tian B., Yang J., Zhao L., Wu X., Ye S.-L., Liu Y.-K., Tang Z.-Y.
Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics.
J. Cancer Res. Clin. Oncol. 130:460-468(2004)

PubMed=23505090; DOI=10.1002/hep.26402
Wang K., Lim H.Y., Shi S., Lee J., Deng S., Xie T., Zhu Z., Wang Y., Pocalyko D., Yang W.J., Rejto P.A., Mao M., Park C.-K., Xu J.
Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma.
Hepatology 58:706-717(2013)

PubMed=32884988; DOI=10.1016/j.gendis.2019.12.008
Lin Y.-L., Li Y.
Study on the hepatocellular carcinoma model with metastasis.
Genes Dis. 7:336-350(2020)