SCLC-1（non-SMC） Mouse small cell lung cancer cells

Mouse models with Trp53-floxed (L) and Rb1-floxed (L) conditioned knockout were obtained through hybridization. Mice were administered nasal drops of adenovirus Cre recombinase (Ad-Cre) to knock out Trp53 and Rb1 in lung epithelial cells. Lung small cell lung cancer (SCLC) tumors were collected 6-8 months after treatment, and mouse small cell lung cancer (mSCLC) cell lines were established. Based on NCAM and CD44 expression, the NCAMloCD44hi population was named non-metastatic SCLC cells (non-SMC). It has been reported that these cells can form tumors in immunodeficient mice. These cells were established by the team led by Researcher Ji Hongbin at the Center for Excellence in Molecular and Cell Science, Chinese Academy of Sciences, and transferred to our database, which designated our database as the sole channel for sharing cell resources.

Animal Species: Mouse

Tissue Source:Mouse small cell lung cancer tissue

Morphology:Wall-pressed

Culture Medium Formula:RPMI-1640 Complete Medium（MD0201）

Gas phase: Air, 95%; Carbon dioxide, 5%. Temperature: 37℃. 

Freezing conditions:  90% FBS (SD0200) + 10% DMSO

Complete cryopreservation solution: No Programmed Cryopreservation Cells Solution (low Serum)(SD0001)

Declaration: The product is for scientific research purposes only.