LA795 [LA-795] Mouse lung cancer cells

Mouse lung adenocarcinoma cells LA795, also known as LA-795. This cell originates from the transplantable lung adenocarcinoma LA-795 strain, which Chinese scientists established in May 1979 in the inbred mouse T739 as a transplantable lung adenocarcinoma with spontaneous metastatic characteristics. Cells of this tumor strain were inoculated into homogeneous mice for subcutaneous transplantation and passaging, with a 100% lung metastasis rate and no spontaneous regression. The LA-795 tumor strain was cultured in vitro primary; cells began to grow after 24 hours, with epithelial-like round cells appearing 45 days after the first passage. After 108 passages over three years, growth stabilized, and it was named LA-795. The cell karyotype is subtetraploid, with chromosome modes of 69, 68, 67, and 66. These cells were successfully subcutaneously transplanted into mouse strains such as T739, 615, and KM, with a 100% lung metastasis rate in T739 mice, commonly used in lung cancer research, drug screening, and vaccine development.

Animal Species: Mouse

Tissue Source:Lungs; Disease: adenocarcinoma

Morphology:epithelial, grows adherently

Culture Medium Formula:RPMI-1640 Complete Medium（MD0201）

Gas phase: Air, 95%; Carbon dioxide, 5%. Temperature: 37℃. 

Freezing conditions:  90% FBS (SD0200) + 10% DMSO

Complete cryopreservation solution: No Programmed Cryopreservation Cells Solution (low Serum)(SD0001)

Declaration: The product is for scientific research purposes only.

PubMed=3250825
Li-Hua Ling, Shu-Hua Song, Zhao-Wei Zhang;
Chromosome of transplantable lung adenocarcinoma cell line (LA-795).
Zhonghua Zhong Liu Za Zhi 10:406-409(1988)

PubMed=2249590
San-Duo Xu, Jin Gao;
Invasion of mouse lung adenocarcinoma (LA795) cell aggregates transplanted into auricle of syngenic T739 mice.
Zhonghua Zhong Liu Za Zhi 12:186-189(1990)