EOMA Mouse vascular endothelioma cells

EOMA is a mouse hemangioendothelioma cell line, isolated in 1980 from adult mice with angioendothelioma, and can be used for cardiovascular disease research. EOMA cells exhibit typical endothelial features, such as rearranging on a matrigel to form tubular structures, and maintaining a pebble-like shape during cell convergence. Its in vitro behavior is highly similar to that of microvascular endothelial cells. It is a commonly used in vitro model in vascular biology and tumor angiogenesis research, combining endothelial cell characteristics with tumor cell characteristics. In homogeneous mice, 100% are tumorigenic, forming vascularly rich tumor tissue. With their stable endothelial phenotype and tumorigenesis capabilities, EOMA cells have become important tools connecting basic vascular biology with tumor angiogenesis research, providing a reliable in vitro platform for mechanistic analysis and treatment strategy development of vascular-related diseases.

Animal Species: Mouse

Tissue Source:Vascular endothelium, mixed vascular endothelioma

Morphology:Epithelial cells grow adherently

Culture Medium Formula:DMEM (high Sugar) Complete Medium（MD0101）

Gas phase: Air, 95%; Carbon dioxide, 5%. Temperature: 37℃. 

Freezing conditions:  90% FBS (SD0200) + 10% DMSO

Complete cryopreservation solution: No Programmed Cryopreservation Cells Solution (low Serum)(SD0001)

Declaration: The product is for scientific research purposes only.

PubMed=2166185
Jorge L. Obeso, Joanne Weber, Robert Auerbach;
A hemangioendothelioma-derived cell line: its use as a model for the study of endothelial cell biology.
Lab. Invest. 63:259-269(1990)