MKN7 [MKN-7; MKN 7] Human gastric cancer cells

MKN7 [MKN-7; The MKN7] cell line was established by Hojo et al. in 1989, derived from a well-differentiated primary site of gastric tubular adenocarcinoma or lymph node metastases in a 39-year-old male patient. This cell is highly expressive of c-erbB2 (HER2), commonly has TP53 mutations (to be verified), and is microsatellite stable (MSS). Compared to other gastric cancer cell lines (such as MKN-1), fibrinolytic activity is low and thrombotic activity is weaker, indicating relatively low invasiveness. It can be used to study the mechanisms of gastric cancer occurrence and development, and to evaluate the efficacy of anticancer drugs (such as HER2-targeted drugs).

Animal Species: Human

Tissue Source:Gastric tubular adenocarcinoma

Morphology:Epithelial cells, adherent growth

Culture Medium Formula:RPMI-1640 Complete Medium（MD0201）

Gas phase: Air, 95%; Carbon dioxide, 5%. Temperature: 37℃. 

Freezing conditions:  90% FBS (SD0200) + 10% DMSO

Complete cryopreservation solution: No Programmed Cryopreservation Cells Solution (low Serum)(SD0001)

Declaration: The product is for scientific research purposes only.

CLPUB00581
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