K562-s Human chronic myeloid leukemia cells

Human chronic myeloid leukemia cells K562-s are clones isolated in 1999 from the parent cell K-562 [K562, K562], and exhibit blood cell morphology. The parent K-562 was isolated and established from the pleural fluid of a terminally ill 53-year-old female patient with chronic myeloid leukemia. K562-s also contains a BCR/ABL fusion gene. This cell is sensitive to the tyrosine kinase inhibitor imatinib mesylate and can pair with imatinib-resistant strain K562-r. It serves as an important cellular model for studying targeted therapy and resistance mechanisms in chronic medullenic leukemia, and is applied in immune system disease research.

Animal Species: Human

Tissue Source:Bone marrow; From metastatic lesions: pleural effusion; Disease: Chronic myeloid leukemia

Morphology:Lymphoblast-like, suspended growth

Culture Medium Formula:RPMI-1640 Complete Medium（MD0201）

Gas phase: Air, 95%; Carbon dioxide, 5%. Temperature: 37℃. 

Freezing conditions:  90% FBS (SD0200) + 10% DMSO

Complete cryopreservation solution: No Programmed Cryopreservation Cells Solution (low Serum)(SD0001)

Declaration: The product is for scientific research purposes only.