RPMI 2650 Human nasal cavity epithelial cells

The human RPMI-2650 cell line was derived from tissue samples of squamous cell carcinoma with nasal septal dysplasia obtained from a 52-year-old male patient. Initially isolated from the patient's pleural effusion, this cell line originates from metastatic lesions. RPMI-2650 exhibits unique genetic characteristics: it possesses a near-diploid karyotype with stable chromosome number, likely arising from malignant cells yet exhibiting a nearly normal karyotype, making it an ideal model for studying tumor cytogenetics. As a human-derived immortalized nasal epithelial cell line, RPMI-2650 serves as the gold-standard in vitro model for investigating nasal-brain delivery and nasal drug administration, and is also applicable to respiratory virology studies as well as 3D culture and organ-on-a-chip research.

Animal Species:Human

Tissue Source: Nose

Morphology:Epithelioid, polygonal, adherent growth

Culture Medium Formula:MEM Complete Medium（MD0301）

Gas phase: Air, 95%; Carbon dioxide, 5%. Temperature: 37℃. 

Freezing conditions:  90% FBS (SD0200) + 10% DMSO

Complete cryopreservation solution: No Programmed Cryopreservation Cells Solution (low Serum)(SD0001)

Declaration: The product is for scientific research purposes only.

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