Mouse SV40 Immortalized Sinusoidal Endothelial Cell Line

Background: Hepatic Sinusoidal Endothelial Cells (HSECs) Are An Unique Sub Population Of Liver That Lines The Heptic Sinusoids Their Role Involves In Clearing Waste Products From The Blood, Regulating Pericyte Contractility And Innate Immune Functions.  The Immortalised Mouse Hepatic Sinusoidal Endothelial Cells- SV40 Is Derived From C57BL/6 Mouse HSECs That Have Maintained Endothelial Characteristics And HSEC-specific Features Such As VWF And Caveolin-1.  These Cells Also Migrate In Response To Angiogenici Growth Factors, Form Vascular Tube-like Structures, Endycytose Acetylated Low-density Lipoprotein (AcLDL) And Secrete Proteins Involved In Matrix Remodelling.  In Addition, These Cells Are Easily Transduced By Retrovirus.  The Immortalized Mouse Hepatic Sinusoidal Endothelial Cells - SV40 Is More Suitable For Studying Liver Endothelial Cell Biology, Including Mobility And Angiogenesis. Their Functions Include Removing Wastes From The Blood, Regulating Pericyte Contractility And Innate Immune Function. Mouse Sinusoidal Endothelial Cells SV40 Are Derived From C57BL/6 Mouse HSECs, Which Maintain Endothelial Cell Characteristics And HSECs Specific Characteristics, Such As VWF And Caveolin-1. These Cells Also Migrate In Response To Angiogenic Growth Factors, Form Vascular Tubular Structures, Acetylate Low-density Lipoprotein (AcLDL), And Secrete Proteins Involved In Matrix Remodeling. In Addition, These Cells Are Easily Transduced By Retroviruses. Therefore, Mouse Sinusoidal Endothelial Cells - SV40 Are Suitable For Studying The Biology Of Liver Endothelial Cells, Including Motility And Angiogenesis. Animal Species/Oganism & Nbsp; Mouse Tissue Source; Tissue And Cell Type  Morphology Of Sinusoidal Endothelial Cells; Endothelial Cell Like, Adherent Growth & Nbsp; Note: This Product Is Only For Scientific Research