Human Pancreatic Duct Epithelial Cell Line (H6c7)

Background: H6c7 Is An Embedded Authentic Cell Line Derived From Normal Human Pancreatic Duct Authentic (HPDE) Cells This Cell Line Is An Attractive Model For Human Pancreatic Duct Cell Carcinogenesis Studies.HighlightsDemonstrate Near Normal Genotype And Phenotype Of HPDE CellsDisplay Copy Number Of P16INK4A Gene, Wild Type P53 And KRAS GenesMorphologically Similar To The Primary HPDE Cells,  Grow Anchorage-dependently And Do Not Form Tumors In Scid MiceGrowth Remains Inhibited By Transforming Growth Factor (TGF)-beta 1。 H6c7 Is An Immortalized Epithelial Cell Line Derived From Normal Human Pancreatic Duct Epithelial Cells (HPDE). This Cell Line Is An Attractive Model To Study Carcinogenesis Of Human Pancreatic Duct Cells. It Is Highlighted That In Scid Cells, HPDE Cells Are Close To Normal Genotypes And Phenotypes, Showing The Copy Number Of P16INK4A Gene. The Morphology Of Wild Type P53 And KRAS Genes Is Similar To That Of Primary HPDE Cells. They Depend On Fixed Growth, Do Not Form Tumors, And Their Growth Is Still Inhibited By Transforming Growth Factor (TGF) - 1. Animal Species/Oganism & Nbsp; People Organization Source; Tissue And Cell Type  Morphology Of Pancreatic Duct Epithelial Cells; Epithelial Cell Like, Adherent Growth& Nbsp; Note: This Product Is Only For Scientific Research