16HBE14o Human Bronchial Epithelial Cell Line

Background:/context: 16HBE14o - Is A Human Bronchial Epithelial Cell Line Isolated From A 1-year Old Male Heart Lung Patient And Modernized With The Origin Of Replication Defective SV40 Plasma (pSVori -) The Cell Line Retains Characteristic Features Of Normal Differentiated Bronchial Epithelial Cells Including A Cobblestone Morphology, Cytokeratin Expression, The Ability To Form Tight Junctions, And Directional Ion Transport.  When Grown With An Air/liquid Interface, Cilia Can Be Detected.  In Contrast To Most Other Respiratory Cell Lines, 16HBE14o- Expresses High Levels Of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) MRNA And Protein.  Expression Of CFTR Is Correlated To CAMP Dependent Cl - Conductivity In A Variety Of Cells, Including 16HE14o - Epithelial Cells.16HBE14o - Is A Human Bronchial Epithelial Cell Line Isolated From A 1-year-old Male Heart And Lung Patient, With Replication Origin Defect SV40 Plasmid (pSVori -). This Cell Line Retains The Characteristics Of Normally Differentiated Bronchial Epithelial Cells, Including Pebble Like Morphology, Cytokeratin Expression, The Ability To Form Tight Junctions, And Directional Ion Transport. When Growing At An Air/liquid Interface, Cilia Can Be Detected. Compared With Most Other Respiratory Cell Lines, 16HBE14o Expresses High Levels Of Cystic Fibrosis Transmembrane Conductance Regulation (CFTR) MRNA And Protein. CFTR Expression Is Associated With Camp Dependent Cl Conductance In A Variety Of Cells, Including 16HE14o Epithelial Cells. Animal Species/Oganism & Nbsp; People Organization Source; Tissue And Cell Type  Morphology Of Bronchial Epithelial Cells; Epithelial Cell Like, Adherent Growth& Nbsp; Note: This Product Is Only For Scientific Research